Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 GenomicAlterations CGI

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib. 18199554

2008

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. 18458038

2008

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Comparing ICA-based and single-trial topographic ERP analyses. 20422446

2010

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy. 19147750

2009

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Second-line treatments after first-line gefitinib therapy in advanced nonsmall cell lung cancer. 19536777

2010

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor: results of a phase II trial in patients with advanced non-small-cell lung cancer. 20479403

2010

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer. 19922469

2010

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. 15738541

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Non-responsiveness to gefitinib in a patient with lung adenocarcinoma having rare EGFR mutations S768I and V769L. 17045698

2006

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Mutations in the tyrosine kinase domain of the EGFR gene associated with gefitinib response in non-small-cell lung cancer. 16011858

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response. 18676761

2008

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Effects of marine oil-enriched diets on guinea pig megakaryocyte and platelet lipids: effects on thromboxane synthesis and platelet function. 2302402

1990

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring rare epidermal growth factor receptor mutations. 21841502

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR "Effectiveness of tyrosine kinase inhibitors on ""uncommon"" epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer." 21531810

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Prognostic factors for gefitinib-treated postoperative recurrence in non-small cell lung cancer. 18176089

2007

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. 16187797

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. 15623594

2004

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. 16533793

2006

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants. 16205628

2006

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. 15710947

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Good clinical response to gefitinib in a non-small cell lung cancer patient harboring a rare somatic epidermal growth factor gene point mutation; codon 768 AGC > ATC in exon 20 (S768I). 20522446

2010

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.700 CausalMutation CLINVAR Prognostic implication of EGFR, KRAS, and TP53 gene mutations in a large cohort of Japanese patients with surgically treated lung adenocarcinoma. 19096302

2009